The PAS fold

PAS domain of the Aer redox sensor requires C-terminal residues for native-fold formation and flavin adenine dinucleotide binding.

The Aer protein in Escherichia coli is a membrane-bound, FAD-containing aerotaxis and energy sensor that putatively monitors the redox state of the electron transport system. Binding of FAD to Aer requires the N-terminal PAS domain and residues in the F1 region and C-terminal HAMP domain. The PAS domains of other PAS proteins are soluble in water. To investigate properties of the PAS domain, we...

Setting the PAS, the role of circadian PAS domain proteins during environmental adaptation in plants

The per-ARNT-sim (PAS) domain represents an ancient protein module that can be found across all kingdoms of life. The domain functions as a sensing unit for a diverse array of signals, including molecular oxygen, small metabolites, and light. In plants, several PAS domain-containing proteins form an integral part of the circadian clock and regulate responses to environmental change. Moreover, t...

n-fold Commutative Hyper K-ideals

 In this paper, we aresupposed to introduce the definitions of n-fold commutative, andimplicative hyper K-ideals. These definitions are thegeneralizations of the definitions of commutative, andimplicative hyper K-ideals, respectively, which have been definedin [12]. Then we obtain some related results. In particular wedetermine the relationships between n-fold implicative hyperK-ideal and n-fol...

Para-Aminosalicylic Acid: Pas

Pas de Deux

The implementation of thyroid hormone (T3) or glucagon as lipid-lowering, antidiabetic, and antiobesity agents have not been successful to date because of serious adverse side effects. Using a synthetic hybrid glucagon/T3 conjugate, Finan et al have established a novel therapeutic approach for the reversal of dyslipidemia, obesity, and insulin resistance associated with the metabolic syndrome, ...